Mieloma múltiple en pacientes con lupus eritematoso sistémico: presentación de dos casos / Multiple myeloma in systemic lupus erythematosus: report of two cases

There is an increased incidence of hematological malignancies, particularly non-Hodgkin lymphoma (NHL) in systemic lupus erythematosus (SLE). In contrast, the concurrence with Multiple Myeloma (MM) is very rare, and the possible pathogenetic mechanisms underlying this association remain unclear. We report two patients who developed MM 15 and four years after being diagnosed as having SLE.

Trombosis intra-cardíaca en síndrome antifosfolípido primario: comunicación de un caso / Intracardiac thrombosis in primary antiphospholipid syndrome: report of 1 case

Antiphospholipid antibody syndrome is characterized by arterial or venous thrombosis associated to the presence of antiphospholipid antibodies. We report a 32 years old male who presented with an erterial thrombosis, and echocardiogram disclosed an atrial thrombus. Four months later, being with anticoagulant treatment, he had a deep venous thrombosis. A new echocardiogram did not show the atrial thrombus. The laboratory work-up confirmed an antiphospholipid syndrome. Five months later the patient has not presented new thrombotic episodes and is receiving oral anticoagulants and antiplatelet therapy